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lipofuscinosis [ lip″o-fu″sin-o´sis] any disorder due to abnormal storage of lipofuscins. neuronal ceroid-lipofuscinosis any of several genetic lipidoses characterized by progressive neurodegeneration, loss of vision, and a fatal course; included are janský-bielschowsky disease, vogt-spielmeyer disease, and kufs' disease. filexlib. This description of ceroid-lipofuscinosis, neuronal 5 disease in an Arab family adds to the clinical and molecular diversity of the variant late-infantile neuronal ceroid lipofuscinoses, which Archives of Disease in Childhood - A global paediatric journal - BMJ Sharing of PPT mutations between distinct clinical forms of neuronal ceroid lipofuscinoses in patients from Scotland
La lipofuscinosis neuronal ceroidea consiste en la acumulación de un material anormal llamado lipofuscina en el cerebro. Se piensa que la NCL es causada por problemas con la capacidad del cerebro para eliminar y reciclar proteínas. Las lipofuscinosis se heredan como rasgos autosómicos recesivos.
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The disease was defined as ceroid-lipofuscinosis, and resembled a previously reported case in an adult dachshund. A lysosomal storage disease with accumulation of periodic acid-Schiff- and Sudan black-positive autofluorescent granules in neurons occurred in one 51/2- and one 7-year-old dachshund. A lysosomal storage disease with accumulation of
Adultceroid lipofuscinosis neuronal ceroid lipofuscinosis. Eur Neurol 1979;18: 234-42. 3 DomR,BrucherJM,CeuterickC,CartonH,MartinJJ. Adult ceroid-lipofuscinosis (Kufs' disease) in two brothers. Retinal and visceral storage in one; diag-nostic muscle biopsy in the other. Acta Neuropathol (Berl) 1979;45:67-72. 4 Pratt H,Starr A,AmlieRN,Politoske
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Classic infantile CLN1 disease was previously called infantile neuronal ceroid lipofuscinosis or Santavuori disease. The NCLs are characterized by abnormal accumulation of certain fatty, granular substances (i.e., pigmented lipids [lipopigments] ceroid and lipofuscin) within nerve cells (neurons) of the brain as well as other tissues of the
Classic infantile CLN1 disease was previously called infantile neuronal ceroid lipofuscinosis or Santavuori disease. The NCLs are characterized by abnormal accumulation of certain fatty, granular substances (i.e., pigmented lipids [lipopigments] ceroid and lipofuscin) within nerve cells (neurons) of the brain as well as other tissues of the
Lipofuscin appears to

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