Blood clotting mechanism pdf

The interpretation of the coagulation process described by MacFarlane2 in 1964 (the "MacFarlane cascade") has been of use for many years in beginning to to limit the clotting process. When the gene is mutated, a clot continues to grow larger than needed. This is the most common genetic cause of blood clots. PDF | The authors propose that hemostasis occurs in a stepwise process, regulated by cellular components in vivo. The effectiveness of hemostasis in. prolongation of the clotting time is directly proportional to the concentration of of the regulation of coagulation by the pathway involving Protein C,