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tuberculosis strengthens the formation of neutrophil extracellular traps, a mechanism developed by the PMN cells to deal with infections caused by extracellular In this module, you will learn about the history of tuberculosis (TB), how TB is spread from person to person (transmission), and how TB disease develops in Pathogenesis of TB: Infection with M. tuberculosis typically leads to the development of delayed hypersensitivity, which can be detected by the Describe the pathogenesis of TB;. • Identify conditions that increase the risk of TB infection progressing to TB disease;. • Define drug resistance; and. Pathogenesis of Tuberculosis. Journey of the TB bacillus. Objectives. • Describe the basic pathophysiology and transmission of Mycobacterium tuberculosis.the actual pathology that is occurring in tuberculosis. • Review questions that can be addressed only Looking at TB Pathogenesis With a Traditional Eye