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PDF | Investigations of Phytochemical investigation of the methanol extract of the aerial parts of Polygonum glabrum afforded one new natural product ( − )-2-methoxy-2-butenolide-3-cinnamate 1Department of pharmaceutical chemistry GITAM Institute of Pharmacy GITAM University, Andhra pradesh, India. A b s t r a c t Polygonum glabrum amphibious shrub Various parts of the plant medicine. Traditionally, different decoctions/infusions given for the treatment of rheumatism, jaundice, piles etc. From pharmacological point, the plant has been effectively screened for antihepatotoxic Arthritis was induced using FCA, and the anti-arthritic effect of the ethanolic extract of P.glabrum was studied at doses of250 and500 mg/kg. The effects were compared with those of indomethacin (10 mg/kg). At the end of the study, theliver enzyme levels were determined and a radiological examination was carried out. identified as Polygonum glabrum willd. Belonging to family Polygonaceae (Mishra, 1982) are sold as Rasna. The drug has been the subject of some chemical (Adinarayana, 1980; Tiwari et al, 1979) and pharmacological (Singh et al, 1985) investigations also. In the pharmacognostic field Prakash et al, (in Press) have worked on stem of Polygonum
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